What are the drawbacks of quantum mechanics?

A person is able to consider values in the atomic world that cannot directly ociate with the "macro-world" due to "probability" making them invalid. It is like a person thinking that it is possible for all atoms within a completely closed box to move all to one side and there being none left on the other. "Probability" excludes this. What is proposed in the atomic world and what is workable in the "real world" cannot transpose.